Arrhythmogenic Right Ventricular Cardiomyopathy and Fatty Replacement of the Right Ventricular Myocardium

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Arrhythmogenic right ventricular cardiomyopathy and fatty replacement of the right ventricular myocardium: are they different diseases?

BACKGROUND The relationship between arrhythmogenic right ventricular cardiomyopathy (ARVC) and pure fat replacement of the right ventricle is unclear. METHODS AND RESULTS Myocardial thickness, epicardial fat thickness, percent fibrosis, and intramyocardial fat infiltration were measured in 16 sections each from 25 hearts with typical (fibrofatty) ARVC, 7 hearts with fat replacement of the rig...

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Arrhythmogenic Right Ventricular Cardiomyopathy

Arrythmogenic right ventricular (RV) cardiomyopathy (ARVC) is a cardiomyopathy characterized pathologically by fibrofatty replacement primarily of the RV and clinically by life-threatening ventricular arrhythmias in apparently healthy young people. The prevalence of the disease has been estimated at 1 in 5,000 individuals, although this estimate will likely increase as awareness of the conditio...

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Arrhythmogenic right ventricular cardiomyopathy.

Arrhythmogenic right ventricular cardiomyopathy (ARVC) has evolved from postmortem pathology at to a diagnosable clinical condition, and holds promise for definitive genetic diagnosis. Its prevalence is between 1/1,000 and 1/5,000, with 10% of deaths occurring before age 19 and 50% before age 35. When analyzed against age-specific norms, the electrocardiography (ECG) and signal-averaged ECG (SA...

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Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia1

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by the patchy replacement of myocardium by fatty or fibrofatty tissue. These changes lead to structural abnormalities including right ventricular enlargement and wall motion abnormalities that can be detected by echocardiography, angiography, and cine MRI. ARVC/D is a genetically heterogeneous disorder, since it...

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Arrhythmogenic right ventricular dysplasia/cardiomyopathy.

The heart is a 4-chambered pump that propels blood simultaneously to the lungs and the rest of the body by means of coordinated muscular contraction. Various diseases can affect the heart muscle and cause it to become weak, thus decreasing its ability to pump blood adequately. Disease that weakens the heart muscle is called cardiomyopathy. Some causes of cardiomyopathy are viral infections of t...

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ژورنال

عنوان ژورنال: Circulation

سال: 1998

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.97.16.1571